| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 12/04/25 20.30 | Toronto FC | Minnesota United FC | 0:0 |
| 12/04/25 20.45 | Atlanta United FC | New England Revolution | 0:1 |
| 12/04/25 22.30 | Orlando City | New York Red Bulls | 0:0 |
| 13/04/25 01.30 | New York City FC | Philadelphia Union | 1:0 |
| 13/04/25 01.30 | CF Montreal | Charlotte FC | 0:1 |
| 13/04/25 01.30 | D.C. United | Cincinnati FC | 0:1 |
| 13/04/25 01.30 | Vancouver Whitecaps | Austin FC | 5:1 |
| 13/04/25 02.30 | Nashville SC | Real Salt Lake | 2:1 |
| 13/04/25 02.30 | FC Dallas | Seattle Sounders | 0:1 |
| 13/04/25 03.30 | Colorado Rapids | San Diego FC | 3:2 |
| 13/04/25 04.30 | Los Angeles FC | San Jose Earthquakes | 2:1 |
| 13/04/25 04.30 | Los Angeles Galaxy | Houston Dynamo | 1:1 |
| 13/04/25 20.15 | Sporting Kansas City | Portland Timbers | 2:4 |
| 13/04/25 22.30 | Chicago Fire | Inter Miami CF | 0:0 |
| 14/04/25 01.00 | St. Louis City SC | Columbus Crew | 1:2 |